Postdoctoral Researcher IncaRNAto lab (1.0 FTE)

Department

Faculty of Science and Engineering

Organisation

Rijksuniversiteit Groningen, University of Groningen, V24.0518

Job description

Applications are invited for a fully-funded Postdoctoral researcher position for two years in the research group of Dr. Danny Incarnato, at the Groningen Biomolecular Sciences and Biotechnology Institute (GBB) of the University of Groningen (the Netherlands), to investigate RNA structural ensemble dynamics in living cells.

What
The successful applicant will work on a multidisciplinary project aimed at characterizing the role of RNA structural ensemble dynamics in driving cell fate decision. Particularly, (s)he will

- Develop novel methods for the mapping of RNA ensemble dynamics in living cells.
- Identify regulatory RNA switches involved in cell fate determination using both cancer cell lines and embryonic stem cell models of cell differentiation.
- Design and screen therapeutics for the modulation of RNA structural ensembles.

Where
Founded in 1614, the University of Groningen enjoys an international reputation as a dynamic and innovative center of higher education offering high-quality teaching and research. Flexible study programmes and academic career opportunities in a wide variety of disciplines encourage the 34,000 students and researchers alike to develop their own individual talents. As one of the best research universities in Europe, the University of Groningen has joined forces with other top universities and networks worldwide to become a truly global center of knowledge.

The IncaRNAto lab is hosted in the prestigious Groningen Biomolecular Sciences and Biotechnology Institute (GBB), located in the Zernike Campus, at the northern edge of the city of Groningen.
The GBB is one of the larger institutes of the Faculty of Science and Engineering (FSE) and provides an excellent environment for top-notch research in the field of biomolecular sciences. Twelve vibrant research groups with strong roots in biophysics, biochemistry & molecular biology, cell biology, chemistry, computational biology, microbiology or genetics are organized in two focal areas: ‘Molecular Mechanisms of Biological Processes’ and ‘Physiology and Systems Biology’.

Requirements

Who
The ideal candidates must be highly motivated, hard-working, ambitious, creative, enthusiastic about RNA and interested in conducting both wet-lab and in silico work. (S)he must

- Hold a PhD in molecular biology, biochemistry, or related disciplines.
- Have experience with basic molecular biology techniques (e.g., qPCR, western blot, cloning, etc.)
- Have experience with mammalian cell work (e.g., culture of cell lines and primary cells, transfection, etc.)
- Have experience with RNA-related techniques (e.g., in vitro transcription, Northern blot, PAGE, RT-qPCR, RNA immunoprecipitation, etc.)
- Prior experience working with RNA structure and NGS, as well as experience in bioinformatics and data analysis (i.e. R, Python, Perl) is a significant plus.

Conditions of employment

Contract length: 24 months.

We offer you in accordance with the Collective Labour Agreement for Dutch Universities

- A salary of € 4,020 gross per month (salary scale 10.4 Dutch Universities) based on a full-time position (1.0 FTE), depending of relevant work experience after attaining a PhD.
- A gross holiday allowance of 8%.
- A gross 8.3% year-end bonus.
- A position for two years.

Job Application

When You may apply for this position until 2 February 11:59pm / before 3 February 2025 Dutch local time (CET) by means of the application form (click on "Apply" below on the advertisement on the university website). This is a rolling application, therefore the call will stay open until the position has been filled. Deadline There is no official deadline. Applications are accepted until an appropriate candidate has been selected. The University of Groningen strives to be a university in which students and staff are respected and feel at home, regardless of differences in background, experiences, perspectives, and identities. We believe that working on our core values of inclusion and equality are a joint responsibility and we are constructively working on creating a socially safe environment. Diversity among students and staff members enriches academic debate and contributes to the quality of our teaching and research. We therefore invite applicants from underrepresented groups in particular to apply. For more information, see also our diversity policy webpage: https://www.rug.nl/about-ug/policy-and-strategy/diversity-and-inclusion/ Our selection procedure follows the guidelines of the Recruitment code (NVP): https://www.nvp-hrnetwerk.nl/nl/sollicitatiecode and European Commission's European Code of Conduct for recruitment of researchers: https://euraxess.ec.europa.eu/jobs/charter/code We provide career services for partners of new faculty members moving to Groningen. Unsolicited marketing is not appreciated.

Additional information

For additional information, please contact:

Dr Danny Incarnato
[email protected]

In your application, please always include the job opening ID V24.0518

Extra informatie kan worden verkregen via een van de volgende links:

Groningen Biomolecular Science and Biotechnology Institute (GBB) RNA Structural Ensemble Dynamics research group The conditions of employment The city of Groningen

Digital application form