Post-doc Human ex vivo model to study nonalcoholic fatty liver disease (1.0 FTE)


Faculty of Science and Engineering


University of Groningen

Since its foundation in 1614, the University of Groningen has enjoyed an international reputation as a dynamic and innovative centre of higher education offering high-quality teaching and research. Balanced study and career-development paths in a wide variety of disciplines encourage more than 32,000 students and researchers to realize their own potentials. We are truly an international place of knowledge, and belongs to the most prestigious research universities in Europe and the top 100 universities worldwide.

Job description

The Groningen Research Institute of Pharmacy (GRIP) in the Faculty of Science and Engineering (FSE) has a position for a postdoctoral fellow in the Pharmaceutical Technology and Biopharmacy group. We offer a challenging, interdisciplinary research project whose aim it is to develop a microfluidic biological model to study nonalcoholic fatty liver disease, termed Non-Alcoholic SteatoHepatitis (NASH). The objectives of the project are to (1) address the induction of steatosis in the liver utilizing an ex vivo precision-cut liver slice model, and (2) to develop a microfluidic device to study the effect of the effluent of nonalcoholic fatty liver precision-cut liver slices on human effector cells (e.g. fibroblasts and cancer cells), and (3) to identify NASH-specific biomarkers.

You will be working in a stimulating interdisciplinary biomedical team including cell biologists, analytical chemists, and medical clinicians. You will be involved in the supervision of PhD students. There will be close collaboration with the Pharmaceutical Analysis group in GRIP (Prof. Sabeth Verpoorte,Microfluidics) and with the University of Mainz (Prof. Detlef Schuppan, NASH).


You have knowledge of, and research experience in, the biomedical sciences and/or cell biology as evidenced by a successful PhD research project with publications/conference presentations. Creative thinking, initiative, management skills and good verbal and written English proficiency are a necessity. Proficiency in the Dutch language would be an asset, as would be experience with culturing of precision-cut tissue slices. The ideal candidate is enthusiastic, ambitious, and a team player.

Conditions of employment

Contract length: 24 months.

We offer you in accordance with the Collective Labour Agreement for Dutch Universities:
• a salary of € 3.255 gross per month, up to a maximum of € 3,895 gross per month (salary scale 10)
• a holiday allowance of 8% gross annual income
• an 8.3% year-end bonus
• a personal budget of € 1,000 per year is dedicated for additional training and career activities
• a full-time position, for two years (1.0 FTE).

Job Application

Do you meet our qualification criteria? If yes, your application should include:
• CV
• motivation letter
• copy of the PhD diploma or estimated time of graduation
• contact details of 3 academic references.

You can submit your application until 30 January 11:59pm / before 31 January 2020 Dutch local time (CET) by means of the application form (click on "Apply" below on the advertisement on the university website).

We are an equal opportunity employer that values diversity. We have adopted an active policy to increase the number of female scientists across all disciplines of the university. Therefore, women are encouraged to apply. Our selection procedure follows the guidelines of the Recruitment code (NVP), and European Commission's European Code of Conduct for recruitment of researchers,
Unsolicited marketing is not appreciated.

Additional information

For additional information, please contact:

Prof. Peter Olinga
+31 50 3638373

In your application, please always include the job opening ID 220006

Extra informatie kan worden verkregen via een van de volgende links:

Extra information

Digital application form